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Junctophilin Detection Set

CAT: 0223-PSI-1828Size: 1 SetDry Ice: NoHazardous: No
CAT#:0223-PSI-1828Size:1 Set
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
For images please see PDF data sheet
Reactivity
Human
Immunogen
Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.
Clonality
Polyclonal
Type
Detection Sets
Purification
Antibodies are supplied as affinity chromatography purified IgG.
Concentration
Antibody 1 mg/mL
Buffer
PBS containing 0.02% sodium azide.
Shipping Conditions
Blue Ice
Storage Conditions
Stable at 4˚ C for three months, store at -20˚ C for up to one year.
Applications Notes
These polyclonal antibodies can be used for detection of JPH1 - 4 by immunoblot at 1 - 2 μ g/mL, and for detection of JPH1 - 4 by immunohistochemistry at 2.5 - 5 μ g/mL, and Immunoflourescence.
Background Reference 01
Takeshima H, Komazaki S, Nishi M, et al. Junctophilins: a novel family of junctional membrane complex proteins. Mol. Cell. 2000; 6:11-22.
Background Reference 02
Kakizawa S, Kishimoto Y, Hashimoto K, et al. Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity. EMBO J. 2007; 26:1924-33.
Background Reference 03
Nishi M, Sakagami H, Komazaki S, et al. Coexpression of junctophilin type 3 and type 4 in brain. Brain Res. Mol. Brain Res. 2003; 118:102-10.
Background Reference 04
Phimister AJ, Lango J, Lee EH, et al. Conformation-dependent stability of Junctophilin 1 (JP1) and Ryanodine Receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. J. Biol. Chem. 2007; 282:8867-77.
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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MBS6484007-01Junctophilin 3, CT (Junctophilin-3, Junctophilin Type 3, JP-3, Jph3, Jp3) (PE)
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