IRAK Detection Set

• Background:

  For images please see PDF data sheet

• Reactivity:

  Human

• Immunogen:

  Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.

• Clonality:

  Polyclonal

• Type:

  Detection Sets

• Purification:

  Antibodies are supplied as affinity chromatography purified IgG.

• Buffer:

  PBS containing 0.02% sodium azide.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stable at 4˚ C for three months, store at -20˚ C for up to one year.

• Background Reference 01:

  Cao Z, Henzel WJ, and Gao X. IRAK: a kinase associated with the interleukin-1 receptor.Science 1996; 271:1128-31.

• Background Reference 02:

  Muzio M, Ni J, Feng P, et al. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediator of IL-1 signaling. Science 1997; 278:1612-5.

• Background Reference 03:

  Li S, Strelow A, Fontana EJ, et al. IRAK-4: a novel member of the IRAK family with the properties of an IRAK kinase. Proc. Natl. Acad. Sci. USA 2002; 99:5567-72.

• Background Reference 04:

  Kobayashi K, Hernandez LD, Galan JE, et al. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 2002; 110:191-202.

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid