Retrovirus Restriction Factor Detection Set

• Background:

  For images please see PDF data sheet

• Reactivity:

  Human

• Immunogen:

  Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.

• Clonality:

  Polyclonal

• Type:

  Detection Sets

• Purification:

  Antibodies are supplied as affinity chromatography purified IgG.

• Concentration:

  Antibody 1 mg/mL

• Buffer:

  PBS containing 0.02% sodium azide.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stable at 4˚ C for three months, store at -20˚ C for up to one year.

• Background Reference 01:

  Reymond A, Meroni G, Fantozzi A, et al. The tripartite motif family identifies cell compartments. EMBO J. 2001; 20:2140-51.

• Background Reference 02:

  Stremlau M, Owens CM, Perron MJ, et al. The cytoplasmic body component TRIM5a restricts HIV-1 infection in Old World monkeys. Nature 2004; 427:848-53.

• Background Reference 03:

  Hatziioannou T, Perez-Caballero D, Yang A, et al. Retrovirus resistance factors REF1 and Lv1 are species-specific variants of TRIM5a. Proc. Nat’l. Acad. Sci. USA 2004; 101:10774-9.

• Background Reference 04:

  Sakuma R, Noser JA, Ohmine S, et al. Rhesus monkey TRIM5alpha restricts HIV-1 production through rapid degradation of viral Gal polyproteins. Nat. Med. 2007; 13:631-5.

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid