BMPR1A Recombinant Protein

• Background :

  The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290) . The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.

• NCBI Gene ID :

  657

• Swiss Prot :

  P36894

• Accession Number :

  CAA80257

• Tag :

  His Tag

• Type :

  Recombinant Proteins

• Source :

  HEK293 cells

• Field of Research :

  Cancer, Infectious Disease, Obesity, Signal Transduction

• Purity :

  >97% as determined by SDS-PAGE.

• Buffer :

  PBS, pH7.4

• Shipping Conditions :

  Room Temp

• Storage Conditions :

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight :

  15.7 kDa

• Applications Notes :

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name :

  Bone morphogenetic protein receptor, type IA

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Mishina Y, Starbuck MW , et al.,2004, J. Biol. Chem. 279 (26) : 27560–6.

• Background Reference 02 :

  Song L, Fässler R, et al., 2007, Dev Biol. 301 (1) :276-86.

• Other Product Names :

  BMPR-1A, ALK-3, 10q23del, ACVRLK3, CD292, SKR5

• Tested Applications :

  WB

• Species :

  Human

• Physical Properties :

  Lyophilized

• CAS Number :

  9000-83-3