BMPR1A Recombinant Protein

• Background:

  The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290) . The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.

• NCBI Gene ID:

  657

• Swiss Prot:

  P36894

• Accession Number:

  CAA80257

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Cancer, Infectious Disease, Obesity, Signal Transduction

• Purity:

  >97% as determined by SDS-PAGE.

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  15.7 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Bone morphogenetic protein receptor, type IA

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mishina Y, Starbuck MW , et al.,2004, J. Biol. Chem. 279 (26) : 27560–6.

• Background Reference 02:

  Song L, Fässler R, et al., 2007, Dev Biol. 301 (1) :276-86.

• Other Product Names:

  BMPR-1A, ALK-3, 10q23del, ACVRLK3, CD292, SKR5

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3