Mouse Bmpr1a Antibody

• Background:

  On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.

• NCBI Gene ID:

  12166

• Swiss Prot:

  P36895

• Accession Number:

  P36895

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Mouse Bmpr1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-197 amino acids from the Central region of mouse Bmpr1a.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  60 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Bmpr1a

• NCBI Official Name:

  Bone morphogenetic protein receptor type-1A

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Drogat, B., et al. Blood 116 (12) :2141-2151 (2010)

• Background Reference 02:

  Leung, A.W., et al. Dev. Dyn. 239 (9) :2319-2329 (2010)

• Background Reference 03:

  Mira, H., et al. Cell Stem Cell 7 (1) :78-89 (2010)

• Background Reference 04:

  Libusova, L., et al. Development 137 (14) :2297-2305 (2010)

• Other Product Names:

  Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, BMP-2/BMP-4 receptor, Serine/threonine-protein kinase receptor R5, SKR5, CD292, Bmpr1a, Acvrlk3, Bmpr

• Tested Applications:

  WB

• Physical Properties:

  Liquid