Mouse Bmpr1a Antibody

CAT: 0223-58-516Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-516Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.
NCBI Gene ID
12166
Swiss Prot
P36895
Accession Number
P36895
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Bmpr1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-197 amino acids from the Central region of mouse Bmpr1a.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Bmpr1a
NCBI Official Name
Bone morphogenetic protein receptor type-1A
NCBI Organism
Mus musculus
Background Reference 01
Drogat, B., et al. Blood 116 (12) :2141-2151 (2010)
Background Reference 02
Leung, A.W., et al. Dev. Dyn. 239 (9) :2319-2329 (2010)
Background Reference 03
Mira, H., et al. Cell Stem Cell 7 (1) :78-89 (2010)
Background Reference 04
Libusova, L., et al. Development 137 (14) :2297-2305 (2010)
Other Product Names
Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, BMP-2/BMP-4 receptor, Serine/threonine-protein kinase receptor R5, SKR5, CD292, Bmpr1a, Acvrlk3, Bmpr
Tested Applications
WB
Physical Properties
Liquid

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