Products for Research Use Only

SIGLEC6 Recombinant Protein

CAT: 0223-96-692Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-96-692Size:0.1 mg
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Background
Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1) . SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
CAS Number
9000-83-3
NCBI Gene ID
946
Swiss Prot
O43699
Accession Number
AAH35359
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Purity
>92% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
60.3 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Sialic acid binding Ig-like lectin 6
NCBI Organism
Homo sapiens
Background Reference 01
Takei Y., et al., 1997, Cytogenet. Cell Genet. 78:295-300.
Background Reference 02
Patel N., et al., 1999, J. Biol. Chem. 274:22729-22738.
Other Product Names
SIGLEC6, CD327, CD33L, CD33L1, OBBP1, OB-BP1, CDw327
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized