SIGLEC6 Recombinant Protein

• Background:

  Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1) . SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

• NCBI Gene ID:

  946

• Swiss Prot:

  O43699

• Accession Number:

  AAH35359

• Tag:

  C-Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Purity:

  >92% as determined by SDS-PAGE.

• Buffer:

  50 mM tris, 100 mM glycine, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  60.3 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Sialic acid binding Ig-like lectin 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Takei Y., et al., 1997, Cytogenet. Cell Genet. 78:295-300.

• Background Reference 02:

  Patel N., et al., 1999, J. Biol. Chem. 274:22729-22738.

• Other Product Names:

  SIGLEC6, CD327, CD33L, CD33L1, OBBP1, OB-BP1, CDw327

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3