SIGLEC5 Recombinant Protein

• Background:

  Sialic acid-binding Ig-like lectin 5 (SIGLEC5) is also known as CD33 antigen-like 2 (CD33L2), Obesity-binding protein 2 (OB-BP2), CD antigen CD170, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 / CD170 is expressed by monocytic / myeloid lineage cells. SIGLEC-5 / CD33-L2 binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

• NCBI Gene ID:

  8778

• Swiss Prot:

  O15389

• Accession Number:

  AAH29896

• Tag:

  C-Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  Tris with Glycine, Arginine and NaCl, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  73 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Sialic acid binding Ig-like lectin 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cornish A.L., et al., 1998, Blood 92:2123-2132.

• Background Reference 02:

  Patel N., et al., 1999, J. Biol. Chem. 274:22729-22738.

• Background Reference 03:

  Zhuravleva M.A., et al., 2008, J. Mol. Biol. 375:437-447.

• Other Product Names:

  SIGLEC5, OB-BP2, CD170, CD33L2

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3