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SH2D1A Recombinant Protein

CAT: 0223-92-089Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-92-089Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SH2 Domain-Containing Protein 1A, (SH2D1A) contains one SH2 domain and a short tail and is localized in the cytoplasm. SH2D1A is expressed at a high level in the thymus and the lung, with lower expression levels in the spleen and the liver. SH2D1A acts as an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. In addition, SH2D1A mediates interaction between FYN and SLAMF1. It is also thought to regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.
CAS Number
9000-83-3
NCBI Gene ID
4068
Swiss Prot
O60880
Accession Number
O60880
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Immunology
Buffer
Supplied as a 0.2 um filtered solution of 20mM Tris, 150mM NaCl, 10% Glycerol, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
16.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
SH2 domain containing 1A
NCBI Organism
Homo sapiens
Other Product Names
SH2 Domain-Containing Protein 1A, Duncan Disease SH2-Protein, Signaling Lymphocytic Activation Molecule-Associated Protein, SLAM-Associated Protein, T-Cell Signal Transduction Molecule SAP, SH2D1A, DSHP, SAP
Species
Human
Protein ID
119632232
Physical Properties
Liquid

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