SH2D1A Recombinant Protein

• Background:

  SH2 Domain-Containing Protein 1A, (SH2D1A) contains one SH2 domain and a short tail and is localized in the cytoplasm. SH2D1A is expressed at a high level in the thymus and the lung, with lower expression levels in the spleen and the liver. SH2D1A acts as an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. In addition, SH2D1A mediates interaction between FYN and SLAMF1. It is also thought to regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.

• NCBI Gene ID:

  4068

• Swiss Prot:

  O60880

• Accession Number:

  O60880

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Immunology

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM Tris, 150mM NaCl, 10% Glycerol, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  16.3 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  SH2 domain containing 1A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  SH2 Domain-Containing Protein 1A, Duncan Disease SH2-Protein, Signaling Lymphocytic Activation Molecule-Associated Protein, SLAM-Associated Protein, T-Cell Signal Transduction Molecule SAP, SH2D1A, DSHP, SAP

• Species:

  Human

• Protein ID:

  119632232

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3