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PTPRD Recombinant Protein

CAT: 0223-96-942Size: 0.1 mgDry Ice: NoHazardous: No
CAT#:0223-96-942Size:0.1 mg
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Background
Receptor-type tyrosine-protein phosphatase delta is an enzyme that is encoded by the PTPRD gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRD has been shown to interact with PTPRS and liprin-alpha-1. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple tissue specific alternatively spliced transcript variants of this gene have been reported. Mutations in the PTPRD gene are associated with autism, obsessive–compulsive disorder, and breast cancer.
CAS Number
9000-83-3
NCBI Gene ID
5789
Swiss Prot
P23468-1
Accession Number
P23468-1
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Other
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
140 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Receptor-type tyrosine-protein phosphatase delta isoform 1 precursor
NCBI Organism
Homo sapiens
Background Reference 01
Pulido R., etal., 1995, J Biol Chem., 270 (12) : 6722-6728.
Background Reference 02
Mizuno K., et al., 1993, Mol. Cell Biol., 13 (9) : 5513-5523.
Background Reference 03
Wallace MJ., et al., 1998, Mol. Cell Biol., 18 (5) : 2608-2616.
Other Product Names
PTPRD, R-PTP-delta
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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