PTPRD Recombinant Protein

• Background:

  Receptor-type tyrosine-protein phosphatase delta is an enzyme that is encoded by the PTPRD gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRD has been shown to interact with PTPRS and liprin-alpha-1. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple tissue specific alternatively spliced transcript variants of this gene have been reported. Mutations in the PTPRD gene are associated with autism, obsessive–compulsive disorder, and breast cancer.

• NCBI Gene ID:

  5789

• Swiss Prot:

  P23468-1

• Accession Number:

  P23468-1

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Other

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  140 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Receptor-type tyrosine-protein phosphatase delta isoform 1 precursor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Pulido R., etal., 1995, J Biol Chem., 270 (12) : 6722-6728.

• Background Reference 02:

  Mizuno K., et al., 1993, Mol. Cell Biol., 13 (9) : 5513-5523.

• Background Reference 03:

  Wallace MJ., et al., 1998, Mol. Cell Biol., 18 (5) : 2608-2616.

• Other Product Names:

  PTPRD, R-PTP-delta

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3