B7-H5 Recombinant Protein

• Background:

  Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

• NCBI Gene ID:

  74048

• Swiss Prot:

  Q9D659-1

• Accession Number:

  NP_001153044.1

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  19.7kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  V-type immunoglobulin domain-containing suppressor of T-cell activation isoform 2 precursor

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Sakr M.A., et al., 2010, Cancer Sci., 101: 2368-2374.

• Background Reference 02:

  Mayya V., et al ., 2009, Sci. Signal., 2: RA46-RA46.

• Other Product Names:

  B7-H5, SISP1, Gi24, VISTA

• Tested Applications:

  WB

• Species:

  Mouse

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3