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GADD45A Recombinant Protein

CAT: 0223-92-028Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-028Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Growth Arrest and DNA Damage-Inducible Protein GADD45 alpha (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14, GADD45GIP1, PCNA. In T-cells, GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes, stimulating DNA excision repair in vitro and inhibits entry of cells into S phase.
CAS Number
9000-83-3
NCBI Gene ID
1647
Swiss Prot
P24522
Accession Number
P24522
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
20.5 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Growth arrest and DNA damage inducible alpha
NCBI Organism
Homo sapiens
Other Product Names
Growth Arrest and DNA Damage-Inducible Protein GADD45 Alpha, DNA Damage-Inducible Transcript 1 Protein, DDIT-1, GADD45A, DDIT1, GADD45
Species
Human
Physical Properties
Lyophilized

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