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GADD45B Recombinant Protein

CAT: 0223-92-003Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-003Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Growth Arrest and DNA Damage-Inducible Protein GADD45 beta (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of growth and apoptosis. GADD45B reacts to environmental stresses by mediating activation of stress-responsive MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. In addition, GADD45B participates in the down-regulation of hepatocellular carcinoma (HCC) . It may serve as a possible therapeutic target.
CAS Number
9000-83-3
NCBI Gene ID
4616
Swiss Prot
O75293
Accession Number
O75293
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
20 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Growth arrest and DNA damage inducible beta
NCBI Organism
Homo sapiens
Other Product Names
Growth Arrest and DNA Damage-Inducible Protein GADD45 Beta, Myeloid Differentiation Primary Response Protein MyD118, Negative Growth Regulatory Protein MyD118, GADD45B, MYD118
Species
Human
Protein ID
119632232
Physical Properties
Lyophilized

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