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GADD45A Antibody

CAT: 0223-61-503Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-503Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45A gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms.
NCBI Gene ID
1647
Swiss Prot
P24522
Accession Number
P24522
Host
Rabbit
Reactivity
Human
Immunogen
This GADD45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-165 amino acids from the C-terminal region of human GADD45A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Hamster, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
18 kDa
Fragment
Rabbit Ig
Symbol
GADD45A
NCBI Official Name
Growth arrest and DNA damage-inducible protein GADD45 alpha
NCBI Organism
Homo sapiens
Background Reference 01
Li, L.S., J. Biol. Chem. 283 (31), 21394-21403 (2008)
Background Reference 02
Al-Romaih, K., Neoplasia 10 (5), 471-480 (2008)
Background Reference 03
Zhu, Q.S., Cancer Res. 68 (8), 2895-2903 (2008)
Background Reference 04
Kearsey, J.M., Oncogene 11 (9), 1675-1683 (1995)
Other Product Names
Growth arrest and DNA damage-inducible protein GADD45 alpha, DNA damage-inducible transcript 1 protein, DDIT-1, GADD45A, DDIT1, GADD45
Tested Applications
WB, Flow
Protein ID
120751
Physical Properties
Liquid

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