Fetuin B Recombinant Protein

• Background:

  Fetuin-B (FETUB), a second member of the fetuin family in mammals, is also known as Fetuin-like protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuin-B-type domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity) . As a liver-derived plasma protein, FETUB is essential for fertilization.

• NCBI Gene ID:

  26998

• Swiss Prot:

  Q9UGM5

• Accession Number:

  AAH69670

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Neuroscience

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  50 mM Tris, 150 mM NaCl, pH8.0

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  42.4 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Fetuin B

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Olivier E., et al., 2000, Biochem. J. 350:589-597.

• Background Reference 02:

  Dietzel E., et al., 2013, Dev. Cell 25:106-112.

• Background Reference 03:

  Muzny D.M., et al., 2006, Nature 440:1194-1198.

• Other Product Names:

  FETUB, Fetuin-B, 16G2, Gugu

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3