Fetuin A Recombinant Protein

• Background:

  Fetuin A/AHSG is a human plasma glycoprotein belonging to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuin A/AHSG is a major serum protein component that exerts various calcium dependent physiological activities, and can mediate growth signaling in certain tumor cells. It also can act as a natural antagonist against specific TGF-β and BMP signaling proteins, Recombinant human Fetuin-A is a heterodimeric protein containing a 282 amino acid A chain and a 27 amino acid B chain. Due to glycosylation, recombinant Fetuin-A migrates at an apparent molecular weight of 45 - 55 kDa by SDS-PAGE run under non-reducing conditions.

• NCBI Gene ID:

  197

• Swiss Prot:

  P02765

• Accession Number:

  NP_001613.2

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Cancer, Cell Cycle, Immunology, Neuroscience, Obesity, Signal Transduction

• Purity:

  Greater than 98% by SDS-PAGE gel and HPLC analyses.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized Fetuin A recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Fetuin A stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Fetuin A recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Alpha-2-HS-glycoprotein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  AHS, A2HS, HSGA, FETUA, PRO2743, Alpha-2-HS-glycoprotein, Alpha-2-Z-globulin

• Species:

  Human

• Protein ID:

  156523970

• Physical Properties:

  Lyophilized