BCAS2 Recombinant Protein

• Background:

  Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.

• NCBI Gene ID:

  10286

• Swiss Prot:

  O75934

• Accession Number:

  O75934

• Tag:

  C-6 His, N-T7 tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Apoptosis, Cancer, Cell Cycle

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 200mM NaCl, 2mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  28.58 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Breast carcinoma amplified sequence 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Pre-mRNA-Splicing Factor SPF27, Breast Carcinoma-Amplified Sequence 2, DNA Amplified in Mammary Carcinoma 1 Protein, Spliceosome-Associated Protein SPF 27, BCAS2, DAM1

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3