Products for Research Use Only
RegisterLogin

SCH 900822

CAT: 0804-HY-12735Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-12735Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SCH 900822 is a potent and selective glucagon receptor (hGCGR) antagonist that blocks the binding of glucagon to its receptor, thereby reducing hepatic glycogenolysis and gluconeogenesis, thereby lowering blood glucose production. SCH 900822 can be used in the study of type 2 diabetes[1].
CAS Number
1220894-09-6
UNSPSC
12352005
Target
GCGR
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Endocrinology; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sch-900822.html
Smiles
O=C(C1=CC=C([C@@H](CCC(C)(C)C)N([C@]2(N=C3C4=CC(Cl)=CC(Cl)=C4)CC[C@@H](C(C)(C)C)CC2)C3=O)C=C1)NCC5=NN=NN5
Molecular Formula
C34H43Cl2N7O2
Molecular Weight
652.66
References & Citations
[1]DeMong D, et al. The Discovery of N- ((2 H-Tetrazol-5-yl) methyl) -4- ((R) -1- ((5 r, 8 R) -8- (tert-butyl) -3- (3, 5-dichlorophenyl) -2-oxo-1, 4-diazaspiro [4.5] dec-3-en-1-yl) -4, 4-dimethylpentyl) benzamide (SCH 900822) : A Potent and Selective Glucagon Receptor Antagonist[J]. Journal of medicinal chemistry, 2014, 57 (6) : 2601-2610.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-18157SCH 900229
HY-165428-01SCH-900875
HY-105110SCH 39304
HY-N10271SCH 38519
HY-119055Sch 33303
HY-171449SCH 211803
HY-122130SCH 2047069
HY-123397SCH-44643
HY-123392Sch 13835
HY-123280SCH 54388

Alternative Products

CatalogName
MBS5813740SCH-900822

Popular Products