SARS-CoV-2 3CLpro-IN-23

SARS-CoV-2 3CLpro-IN-23

• UNSPSC Description: SARS-CoV-2 3CLpro-IN-23 (Compound Cd3) is a compound that can be isolated from Citrus depressa. SARS-CoV-2 3CLpro-IN-23 has good inhibitory activity to the SARS-CoV-2 spike protein, with KD of 0.79 μM. SARS-CoV-2 3CLpro-IN-23 can bind to key amino acid residue, disrupting the formation of the spike protein and h-ACE2 complex[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-3clpro-in-23.html
• Solubility: 10 mM in DMSO
• Smiles: COC(C=C1)=CC=C1/C=C/C(C2=C(C(OC)=C(C=C2O)OC)OC)=O
• Molecular Weight: 344.36
• References & Citations: [1]Liu TW, et al. Polymethoxyflavone from Citrus depressa as an inhibitor against various variants of SARS-CoV-2 spike protein. J Ethnopharmacol. 2024 Feb 10;320:117412.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported