SARS-CoV-2 3CLpro-IN-23

• UNSPSC Description:

  SARS-CoV-2 3CLpro-IN-23 (Compound Cd3) is a compound that can be isolated from Citrus depressa. SARS-CoV-2 3CLpro-IN-23 has good inhibitory activity to the SARS-CoV-2 spike protein, with KD of 0.79 μM. SARS-CoV-2 3CLpro-IN-23 can bind to key amino acid residue, disrupting the formation of the spike protein and h-ACE2 complex[1].

• Target Antigen:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sars-cov-2-3clpro-in-23.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC(C=C1)=CC=C1/C=C/C(C2=C(C(OC)=C(C=C2O)OC)OC)=O

• Molecular Weight:

  344.36

• References & Citations:

  [1]Liu TW, et al. Polymethoxyflavone from Citrus depressa as an inhibitor against various variants of SARS-CoV-2 spike protein. J Ethnopharmacol. 2024 Feb 10;320:117412.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported