SARS-CoV-2 3CLpro-IN-18

SARS-CoV-2 3CLpro-IN-18

• CAS Number: 3032604-29-5
• UNSPSC Description: SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 0.478 μM). SARS-CoV-2 3CLpro-IN-18 inhibits SARS-CoV-2 in Vero E6 cells (EC50= 2.499 μM) with low cytotoxicity (CC50 > 200 μM)[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-3clpro-in-18.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31)CSC#N
• Molecular Weight: 328.82
• References & Citations: [1]Ren P, et al. Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group. J Med Chem. 2023 Aug 18.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported