SARS-CoV-2 3CLpro-IN-22

SARS-CoV-2 3CLpro-IN-22

• UNSPSC Description: SARS-CoV-2 3CLpro-IN-22 (Compound 17) is a cathepsin L (CTSL ) inhibitor with an IC50 value of 32.5 nM. SARS-CoV-2 3CLpro-IN-22 can be used for the study of SARS-CoV-2 virus[1].
• Target Antigen: Cathepsin; SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-3clpro-in-22.html
• Solubility: 10 mM in DMSO
• Smiles: ClCC(NCC(N[C@H](C(NCC1=CC=CC=C1)=O)CC2=CNC3=C2C=CC=C3)=O)=O
• Molecular Weight: 426.90
• References & Citations: [1]Ciaglia T, et al. Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization[J]. European Journal of Medicinal Chemistry, 2024: 116128.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported