Progranulin modulator-3

Progranulin modulator-3

• CAS Number: 371116-39-1
• UNSPSC Description: Progranulin modulator-3 (compd C40) is a brain-penetrant and orally active progranulin (PGRN) inducer. Progranulin modulator-3 can be used for neurological research[1].
• Target Antigen: Neurotensin Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/progranulin-modulator-3.html
• Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C1=CC=CO1)NC2=CC=C3C(N=C(C4=CC=CC=C4)O3)=C2
• Molecular Weight: 304.30
• References & Citations: [1]Tesla R, et al. Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency. Nat Commun. 2024 Jul 20;15(1):6125.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported