Smurf1 modulator-1

• UNSPSC Description:

  Smurf1 modulator-1 (Compound 20) is a selective inhibitor for Smad ubiquitination regulatory factor 1 (Smurf1), with IC50 of 180 nM[1].

• Target Antigen:

  E1/E2/E3 Enzyme

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/smurf1-modulator-1.html

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O=C1N(C2CCCCC2)N(C(C)=C1NC(C3=NOC([C@H]4[C@@H](OC(C)(CO4)C)C)=C3C)=O)C

• Molecular Weight:

  446.54

• References & Citations:

  [1]A D'souza, et al., Carboxamide derivatives. WO2015175796.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1825371-51-4