Nav1.7 blocker 1

• UNSPSC Description:

  Nav1.7 blocker 1 (example 41) is a Na+ channel (Nav) blocker with an IC50 value of 0.037 μM. Nav1.7 blocker 1 can be used for the study of pain, including neuropathic pain, postoperative pain, inflammatory pain, and so on[1].

• Target Antigen:

  Sodium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/nav1-7-blocker-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NC(C2=CC=C(OC3=CC=C(C=C3)F)C=C2)=NC(N4CCOCC4CO)=C1)N

• Molecular Weight:

  424.42

• References & Citations:

  [1]Chiyou Ni, et al. Pyrimidines as sodium channel blockers. WIPO. Patent. WO2013030665. 2013-03-07

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1426336-36-8