PLpro-IN-2

• Description :

  PLpro-IN-2 (Compound 16) is an inhibitor for SARS-CoV-2 papain-like protease (PLpro), with an IC50 of 0.25 μM[1].

• UNSPSC :

  12352005

• Target :

  SARS-CoV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/plpro-in-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OCC)CCCNCC1=CC=C(C2=CC=CC([C@H](NC(C3=CC(NC4CNC4)=CC=C3C)=O)C)=C2)S1

• Molecular Formula :

  C30H38N4O3S

• Molecular Weight :

  534.71

• References & Citations :

  [1]Wang X, et al., Chemical Space Profiling of SARS-CoV-2 PLpro Using DNA-Encoded Focused Libraries[J]. ACS Medicinal Chemistry Letters, 2024.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported