Verapamil EP Impurity C (hydrochloride)

• UNSPSC Description:

  NSC-609249 hydrochloride is an impurity of Verapamil (HY-14275). Verapamil is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor[1][2].

• Target Antigen:

  Calcium Channel; Cytochrome P450; P-glycoprotein

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/verapamil-ep-impurity-c-hydrochloride.html

• Smiles:

  CN(C)CCC1=CC=C(OC)C(OC)=C1.[H]Cl

• Molecular Weight:

  245.75

• References & Citations:

  [1]Gowarty JL, et al. Verapamil as a culprit of palbociclib toxicity. J Oncol Pharm Pract. 2019 Apr;25(3):743-746.|[2]Krikler DM. Verapamil in arrhythmia. Br J Clin Pharmacol. 1986;21 Suppl 2:183S-189S.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  51012-67-0