KB-R7943

• UNSPSC Description:

  KB-R7943 (compound 1) is an inhibitor of sodium-calcium exchanger with an IC50 value of 5.1 μM. KB-R7943 can be used as a tool in heart and renal failure models[1].

• Target Antigen:

  Na+/Ca2+ Exchanger

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/kb-r7943.html

• Smiles:

  NC(SCCC1=CC=C(OCC2=CC=C([N+]([O-])=O)C=C2)C=C1)=N

• Molecular Weight:

  331.39

• References & Citations:

  [1]Takahiro Kuramochi, et al. Discovery of N-(3-{4-[(3-fluorobenzyl)oxy]phenoxy}propyl)-2-pyridin-4-ylacetamide as a potent and selective reverse NCX inhibitor. Chem Pharm Bull (Tokyo). 2005 Aug;53(8):1043-7.

• Shipping Conditions:

  Room temperature

• CAS Number:

  182004-64-4