KB-R7943

• Description :

  KB-R7943 (compound 1) is an inhibitor of sodium-calcium exchanger with an IC50 value of 5.1 μM. KB-R7943 can be used as a tool in heart and renal failure models[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Na+/Ca2+ Exchanger

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/kb-r7943.html

• Smiles :

  NC(SCCC1=CC=C(OCC2=CC=C([N+]([O-])=O)C=C2)C=C1)=N

• Molecular Formula :

  C16H17N3O3S

• Molecular Weight :

  331.39

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Takahiro Kuramochi, et al. Discovery of N- (3-{4-[ (3-fluorobenzyl) oxy]phenoxy}propyl) -2-pyridin-4-ylacetamide as a potent and selective reverse NCX inhibitor. Chem Pharm Bull (Tokyo) . 2005 Aug;53 (8) :1043-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [182004-64-4]