KB-141

• Description :

  KB-141 is a potent and selective TRβ agonist. The IC50 values are 23.9 nM and 3.3 nM for binding affinities from displacement of T3 from hTRα1 and hTRβ1, respectively. KB-141 has anti-obesity, anti-diabetic, and lipid-lowering effects and can be used as an anti-cholesteremic agent in vivo[1][2].

• UNSPSC :

  12352005

• Target :

  Thyroid Hormone Receptor

• Type :

  Reference compound

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/kb-141.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(CC1=CC(Cl)=C(C(Cl)=C1)OC2=CC=C(C(C(C)C)=C2)O)O

• Molecular Formula :

  C17H16Cl2O4

• Molecular Weight :

  355.21

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [219691-94-8]