Recombinant Human FGF-2/ Basic FGF Protein

Recombinant Human FGF-2/ Basic FGF Protein_x000D_ Catalog number: B2018644_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 ug_x000D_ Molecular Weight or Concentration: ~16 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: FGF-β, basic fibroblast growth factor, bFGF_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Benington LR, Rajan G, Locher C, Lim LY. Stabilisation of Recombinant Human Basic Fibroblast Growth Factor (FGF-2) against Stressors Encountered in Medicinal Product Processing and Evaluation Pharmaceutics. 2021 Oct 21;13(11):1762._x000D_ 2: Morscheid YP, Venkatesan JK, Schmitt G, Orth P, Zurakowski D, Speicher-Mentges S, Menger MD, Laschke MW, Cucchiarini M, Madry H. rAAV-Mediated Human FGF-2 Gene Therapy Enhances Osteochondral Repair in a Clinically Relevant Large Animal Model Over Time In Vivo Am J Sports Med. 2021 Mar;49(4):958-969._x000D_ 3: Lee TH, Kim WT, Ryu CJ, Jang YJ. Optimization of treatment with recombinant FGF-2 for proliferation and differentiation of human dental stem cells, mesenchymal stem cells, and osteoblasts Biochem Cell Biol. 2015 Aug;93(4):298-305._x000D_ 4: Amini M, Venkatesan JK, Nguyen TN, Liu W, Leroux A, Madry H, Migonney V, Cucchiarini M. rAAV TGF-β and FGF-2 Overexpression via pNaSS-Grafted PCL Films Stimulates the Reparative Activities of Human ACL Fibroblasts Int J Mol Sci. 2023 Jul 6;24(13):11140._x000D_ 5: Madry H, Kohn D, Cucchiarini M. Direct FGF-2 gene transfer via recombinant adeno-associated virus vectors stimulates cell proliferation, collagen production, and the repair of experimental lesions in the human ACL Am J Sports Med. 2013 Jan;41(1):194-202._x000D_ 6: Zhang M, Matinlinna JP, Tsoi JKH, Liu W, Cui X, Lu WW, Pan H. Recent developments in biomaterials for long-bone segmental defect reconstruction: A narrative overview J Orthop Translat. 2019 Oct 8;22:26-33._x000D_ 7: Frisch J, Venkatesan JK, Rey-Rico A, Zawada AM, Schmitt G, Madry H, Cucchiarini M. Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates J Exp Orthop. 2016 Dec;3(1):16._x000D_ 8: Valtink M, Knels L, Stanke N, Engelmann K, Funk RH, Lindemann D. Overexpression of human HMW FGF-2 but not LMW FGF-2 reduces the cytotoxic effect of lentiviral gene transfer in human corneal endothelial cells Invest Ophthalmol Vis Sci. 2012 May 31;53(6):3207-14._x000D_ 9: Stehle M, Amini M, Venkatesan JK, Liu W, Wang D, Nguyen TN, Leroux A, Madry H, Migonney V, Cucchiarini M. Commitment of human mesenchymal stromal cells towards ACL fibroblast differentiation upon rAAV-mediated FGF-2 and TGF-β overexpression using pNaSS-grafted PCL films Biotechnol Bioeng. 2024 Jun 14._x000D_ 10: Gasparian ME, Elistratov PA, Drize NI, Nifontova IN, Dolgikh DA, Kirpichnikov MP. Overexpression in Escherichia coli and purification of human fibroblast growth factor (FGF-2) Biochemistry (Mosc). 2009 Feb;74(2):221-5. _x000D_ _x000D_ Products Related to Recombinant Human FGF-2/ Basic FGF Protein can be found at Proteins

9000-83-3

Catalog Number: B2018644 (1 ug)

0.15

2

0.5