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PF-4363467

CAT: 0804-HY-124583Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-124583Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-4363467, a dopamine D3/D2 receptor antagonist, attenuates opioid drug-seeking behavior without concomitant D2 side effects. PF-4363467 exhibits Ki values of 3.1 nM and 692 nM for D3R and D2R[1].
CAS Number
2040055-84-1
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pf-4363467.html
Smiles
CC1=C(NS(=O)(C2=CC=C(C=C2)C(C)C)=O)C=CC([C@@H]3CN(CCO3)CC)=C1
Molecular Formula
C22H30N2O3S
Molecular Weight
402.55
References & Citations
[1]Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects. ACS Chem Neurosci. 2017 Jan 18;8 (1) :165-177.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D2 Receptor; D3 Receptor

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