5-Hydroxy-TSU-68

• Description :

  5-Hydroxy-TSU-68 (compound M1) is the 5-hydroxylated indolinone derivative of TSU-68. TSU-68 is an anticancer agent that inhibits angiogenic receptor tyrosine kinases[1].

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/5-hydroxy-tsu-68.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=C(O)C=C3)=O)=C1C

• Molecular Formula :

  C18H18N2O4

• Molecular Weight :

  326.35

• References & Citations :

  [1]Kitamura R, et, al. Identification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z) -5-[ (1,2-Dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68) . Drug Metabolism and Disposition June 2008, 36 (6) 1003-1009.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [1035154-46-1]