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5-Hydroxy-TSU-68

CAT: 0804-HY-N11675Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N11675Size:1 Each
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Description
5-Hydroxy-TSU-68 (compound M1) is the 5-hydroxylated indolinone derivative of TSU-68. TSU-68 is an anticancer agent that inhibits angiogenic receptor tyrosine kinases[1].
CAS Number
1035154-46-1
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-hydroxy-tsu-68.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=C(O)C=C3)=O)=C1C
Molecular Formula
C18H18N2O4
Molecular Weight
326.35
References & Citations
[1]Kitamura R, et, al. Identification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z) -5-[ (1,2-Dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68) . Drug Metabolism and Disposition June 2008, 36 (6) 1003-1009.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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