7-Hydroxy-TSU-68

• Description :

  7-Hydroxy-TSU-68 is a derivative of TSU-68 (HY-10517) . It is a metabolite of the biotransformation pathway of TSU-68 in human liver microsomes. The content represents the self-induced hydroxylation level of TSU-68[1].

• CAS Number :

  [1035154-52-9]

• UNSPSC :

  12352005

• Target :

  Drug Metabolite

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/7-hydroxy-tsu-68.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=CC=C3O)=O)=C1C

• Molecular Formula :

  C18H18N2O4

• Molecular Weight :

  326.35

• References & Citations :

  [1]Ryuichi Kitamura, et al. Identification of human liver cytochrome P450 isoforms involved in autoinduced metabolism of the antiangiogenic agent (Z) -5-[ (1,2-dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid (TSU-68) . Drug Metab Dispos. 2008 Jun;36 (6) :1003-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported