7-Hydroxy-TSU-68

• Description:

  7-Hydroxy-TSU-68 is a derivative of TSU-68 (HY-10517) . It is a metabolite of the biotransformation pathway of TSU-68 in human liver microsomes. The content represents the self-induced hydroxylation level of TSU-68[1].

• UNSPSC:

  12352005

• Target:

  Drug Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/7-hydroxy-tsu-68.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (O) CCC1=C (C) NC (/C=C2C (NC3=C\2C=CC=C3O) =O) =C1C

• Molecular Formula:

  C18H18N2O4

• Molecular Weight:

  326.35

• References & Citations:

  [1]Ryuichi Kitamura, et al. Identification of human liver cytochrome P450 isoforms involved in autoinduced metabolism of the antiangiogenic agent (Z) -5-[ (1,2-dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid (TSU-68) . Drug Metab Dispos. 2008 Jun;36 (6) :1003-9.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  1035154-52-9