Dentonin (TFA)

• UNSPSC Description:

  Dentonin TFA (AC-100 TFA) is a synthetic fragment derived from MEPE. Dentonin TFA enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin TFA has no significant effect to mature osteoblasts. Dentonin TFA can be used for the research of phosphate homeostasis and bone metabolism[1].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/dentonin-tfa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H](N)[C@@H](C)O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)CCCCN)=O)CC3=CC=CC=C3)=O)CCC2)=O)CCC(N)=O)=O)=O)CC(O)=O)=O)=O)CO)=O)CC4=CC=CC=C4)=O)CCC1)=O)CO)=O)[C@H](CC)C)=O)CC(O)=O)=O)CC(N)=O)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(O)=O.OC(C(F)(F)F)=O

• Molecular Weight:

  2652.61

• References & Citations:

  [1]Andrew P Sprowson, et al. ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion. J Orthop Res. 2008 Sep;26(9):1256-62.|[2]N Six, et al. Dentonin, a MEPE fragment, initiates pulp-healing response to injury.J Dent Res. 2007 Aug;86(8):780-5.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported