Dentonin

CAT: 0804-HY-P2633-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P2633-01Size:5 mg
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Description
Dentonin (AC-100) is a synthetic fragment derived from MEPE. Dentonin enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin has no significant effect to mature osteoblasts. Dentonin can be used for the research of phosphate homeostasis and bone metabolism[1].
CAS Number
[400090-20-2]
Product Name Alternative
AC-100
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dentonin.html
Purity
98.63
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(CCC1)C([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H](CC(N)=O)NC([C@H](CC(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CO)C(NCC(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CCC(N)=O)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CC(O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C107H160N30O42
Molecular Weight
2538.59
References & Citations
[1]Andrew P Sprowson, et al. ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion. J Orthop Res. 2008 Sep;26 (9) :1256-62.|[2]N Six, et al. Dentonin, a MEPE fragment, initiates pulp-healing response to injury.J Dent Res. 2007 Aug;86 (8) :780-5.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported

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