ABBV-467
CAT:
804-HY-149672-01
Size:
10 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ABBV-467
- CAS Number: 2287186-66-5
- UNSPSC Description: ABBV-467 is a selective MCL-1 inhibitor (Ki: apoptosis. ABBV-467 induces cancer cell death and inhibits tumor growth in models of hematological malignancies, such as multiple myeloma[1].
- Target Antigen: Apoptosis; Bcl-2 Family
- Type: Reference compound
- Related Pathways: Apoptosis
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/abbv-467.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(O)[C@@H](CC1=CC2=CC=C1OCC3=NC(C4=CC=C(OC[C@H]5OCCOC5)C=C4)=NC=C3)OC6=NC=NC7=C6C(C8=C(C)C(Cl)=C(O[C@@H](CO2)CN9CCN(C)CC9)C(Cl)=C8C)=C(C%10=CC=C(F)C=C%10)S7
- Molecular Weight: 1037.98
- References & Citations: [1]Yuda J, et al. Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients. Commun Med (Lond). 2023 Oct 25;3(1):154.
- Shipping Conditions: Blue Ice
- Clinical Information: Phase 1