ABBV-318
CAT:
804-HY-146069-06
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ABBV-318
- CAS Number: 1802848-94-7
- UNSPSC Description: ABBV-318 is a potent Nav1.7/ Nav1.8 blocker, with IC50s of 2.8 μM and 3.8 μM for hNav1.7 and hNav1.8, respectively. ABBV-318 can be used for the research of pain[1].
- Target Antigen: Sodium Channel
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/abbv-318.html
- Solubility: DMSO : 166.67 mg/mL (ultrasonic)
- Smiles: O=C(N1C[C@H](F)CC1)C2=NC3=CC=C(OC4=NC=C(C(F)(F)F)C=C4)C=C3C=C2
- Molecular Weight: 405.35
- References & Citations: [1]Patel MV, et, al. Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Na v 1.7/ Nav1.8 blockers for the treatment of pain. Bioorg Med Chem. 2022 Jun 1;63:116743.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported