MAC-0547630

CAT: 0804-HY-119022Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-119022Size:1 Each
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Description
MAC-0547630 is a potent inhibitor of undecaprenyl diphosphate synthase (UppS), with IC50s of 0.05 μM and 1.6 μM for UppSBS and UppSBA, respectively. MAC-0547630 is active against B. subtilis in vitro (MIC 0.1 ng/mL) [1].
CAS Number
[950386-41-1]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mac-0547630.html
Smiles
FC1=CC=C(C2=C(N=C(C)C=C3N4CCCCCC4)N3N=C2)C=C1
Molecular Formula
C19H21FN4
Molecular Weight
324.40
References & Citations
[1]Tomasz L Czarny, et al. A Small-Molecule Screening Platform for the Discovery of Inhibitors of Undecaprenyl Diphosphate Synthase. ACS Infect Dis. 2016 Jul 8;2 (7) :489-99.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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