MAC glucuronide linker-2

• Description:

  MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

• UNSPSC:

  12352203

• Hazard Statement:

  H302, H312, H315, H319, H332, H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mac-glucuronide-linker-2.html

• Purity:

  99.60

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (OC) [C@@H] (O1) [C@@H] (OC (C) =O) [C@H] (OC (C) =O) [C@@H] (OC (C) =O) [C@@H]1OC2=CC=C (CO) C=C2N

• Molecular Formula:

  C20H25NO11

• Molecular Weight:

  455.41

• Precautions:

  H302, H312, H315, H319, H332, H335

• References & Citations:

  [1]Robert A, et al. Compounds, compositions, and methods for treatment of diseases involving acidic or hypoxic diseased tissues. WO2019136298A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Cleavable Linker; Glycosidase Cleavable Linker

• CAS Number:

  229977-57-5