N-Boc-cis-4-Hydroxy-D-proline

CAT:

804-HY-W002887-02

Size:

100 g

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CAS Number: 135042-12-5
UNSPSC Description: N-Boc-cis-4-Hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-Hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the Synthesis of ADCs or PROTACs.
Target Antigen: ADC Linker; PROTAC Linkers
Type: ADC Related
Related Pathways: Antibody-drug Conjugate/ADC Related;PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/n-boc-cis-4-hydroxy-d-proline.html
Purity: 99.96
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: CC(C)(C)OC(N1[C@H](C[C@H](C1)O)C(O)=O)=O
Molecular Weight: 231.248
References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
Shipping Conditions: Room Temperature
Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information: No Development Reported

Cat	Name
HY-W002887-02	N-Boc-cis-4-Hydroxy-D-proline
HY-W002887-01	N-Boc-cis-4-Hydroxy-D-proline
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