IGF-1R/SRC-IN-1

• CAS Number:

  852367-46-5

• UNSPSC Description:

  IGF-1R/SRC-IN-1 (Compound 3b) is an inhibitor for IGF-1R (IC50 is 63 μM) and SRC[1].

• Target Antigen:

  IGF-1R; Src

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/igf-1r-src-in-1.html

• Solubility:

  DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(C(C1=CNC2=C1C=CC=C2)=O)NCC3=CC=C(C)C=C3

• Molecular Weight:

  292.33

• References & Citations:

  [1]Schmidt S, et al., Dual IGF-1R/SRC inhibitors based on a N'-aroyl-2-(1H-indol-3-yl)-2-oxoacetohydrazide structure. Eur J Med Chem. 2011 Jul;46(7):2759-69.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported