SRC-3-IN-1

• UNSPSC Description:

  SRC-3-IN-1 (compound SI-10) is a steroid receptor coactivator 3 (SRC-3) inhibitor (IC50=3.3 μM). SRC-3-IN-1 has good water solubility, oral bioavailability, and improved selectivity profile. SRC-3-IN-1 can be used in prostate cancer research[1].

• Target Antigen:

  Src

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/src-3-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C/C(C1=NC=CC=N1)=N\N=C2N(C3=C(N\2)C=C(F)C(F)=C3)C

• Molecular Weight:

  302.28

• References & Citations:

  [1]Lu D, et al. Lead Compound Development of SRC-3 Inhibitors with Improved Pharmacokinetic Properties and Anticancer Efficacy[J]. Journal of Medicinal Chemistry, 2024, 67(7): 5333-5350.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported