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SRC-3-IN-1

CAT: 0804-HY-163468Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163468Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SRC-3-IN-1 (compound SI-10) is a steroid receptor coactivator 3 (SRC-3) inhibitor (IC50=3.3 μM) . SRC-3-IN-1 has good water solubility, oral bioavailability, and improved selectivity profile. SRC-3-IN-1 can be used in prostate cancer research[1].
UNSPSC
12352005
Target
Src
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/src-3-in-1.html
Solubility
10 mM in DMSO
Smiles
C/C(C1=NC=CC=N1)=N\N=C2N(C3=C(N\2)C=C(F)C(F)=C3)C
Molecular Formula
C14H12F2N6
Molecular Weight
302.28
References & Citations
[1]Lu D, et al. Lead Compound Development of SRC-3 Inhibitors with Improved Pharmacokinetic Properties and Anticancer Efficacy[J]. Journal of Medicinal Chemistry, 2024, 67 (7) : 5333-5350.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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