T338C Src-IN-1

CAT: 0804-HY-16905Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-16905Size:1 Each
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Description
T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C (IC50=111 nM) relative to WT c-Src (10-fold increase) .
CAS Number
[1351926-90-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Src
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/T338C-Src-IN-1.html
Solubility
10 mM in DMSO
Smiles
NC1=C2C(N(C(C)C)N=C2CC3=CC(NS(=O)(C=C)=O)=CC=C3)=NC=N1
Molecular Formula
C17H20N6O2S
Molecular Weight
372.44
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108 (37) :15046-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
MBS3841511-01T338C Src-IN-1
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A16243-25T338C Src-IN-1 25mg
A16243-5T338C Src-IN-1 5mg
A16243-10T338C Src-IN-1 10mg
A16243-50T338C Src-IN-1 50mg
A16243-100T338C Src-IN-1 100mg
MBS3841512-01T338C Src-IN-2
MBS131224T338C-Src-IN-2
A16244-10T338C Src-IN-2 10mg

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