MAP3K20 antibody

CAT: 0710-FNab09581Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab09581Size:100 µg
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AVAILABILITY: InStock
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Background
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM) . This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms
Mitogen-activated protein kinase kinase kinase 20|Human cervical cancer suppressor gene 4 protein (HCCS-4) |Leucine zipper- and sterile alpha motif-containing kinase|MLK-like mitogen-activated protein triple kinase|Mitogen-activated protein kinase kinase kinase MLT|Mixed lineage kinase 7|Mixed lineage kinase-related kinase (MLK-related kinase, MRK) |Sterile alpha motif- and leucine zipper-containing kinase AZK|MAP3K20|MLK7|MLTK|ZAK
Gene ID
51776
UniProt
Q9NYL2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Sterile alpha motif and leucine zipper containing kinase AZK
Target
MAP3K20
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa, 100 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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