Anti-ZAK MAP3K20 Antibody

• Description:

  Boster Bio Anti-ZAK MAP3K20 Antibody catalog # A32464. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Mitogen-activated protein kinase kinase kinase 20

• Gene Name:

  MAP3K20

• UniProt:

  0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human ZAK (NP_598407.1) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  Ubiquitously expressed. Isoform 2 is the predominant form in all tissues examined, except for liver, in which isoform 1 is more highly expressed.

• Applications:

  WB, IHC, ICC, IF

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2 (PubMed:10924358, PubMed:11836244, PubMed:15342622, PubMed:21224381) . Involved in limb development (PubMed:26755636) .

• Molecular Weight:

  91155 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Mitogen-activated protein kinase kinase kinase 20

• Subcellular Location:

  Cytoplasm

• Protein Name:

  Mitogen-activated protein kinase kinase kinase 20