MAP3K5 antibody

• Background:

  ASK1 (Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species (ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase (JNK) and p38.

• Synonyms:

  Mitogen-activated protein kinase kinase kinase 5|Apoptosis signal-regulating kinase 1 (ASK-1) |MAPK/ERK kinase kinase 5 (MEK kinase 5, MEKK 5) |MAP3K5|ASK1|MAPKKK5|MEKK5

• Gene ID:

  4217

• UniProt:

  Q99683

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Mitogen-activated protein kinase kinase kinase 5

• Target:

  MAP3K5

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Immunology, Cardiovascular, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:100-1:1000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  155 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB