MAP3K5 antibody

MAP3K5 antibody

• Background: ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species(ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase(JNK) and p38.
• Synonyms: Mitogen-activated protein kinase kinase kinase 5|Apoptosis signal-regulating kinase 1 (ASK-1)|MAPK/ERK kinase kinase 5 (MEK kinase 5, MEKK 5)|MAP3K5|ASK1|MAPKKK5|MEKK5
• Gene ID: 4217
• UniProt: Q99683
• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Immunogen: mitogen-activated protein kinase kinase kinase 5
• Target: MAP3K5
• Clonality: Polyclonal
• Isotype: IgG
• Applications: ELISA, WB
• Field of Research: Immunology, Cardiovascular, Metabolism
• Purification: Immunogen affinity purified
• Dilution: WB: 1:100-1:1000
• Purity: ≥95% as determined by SDS-PAGE
• Form: Liquid
• Molecular Weight: 155 kDa
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)