VPS37A antibody

• Background:

  This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

• Synonyms:

  Vacuolar protein sorting-associated protein 37A (hVps37A)|ESCRT-I complex subunit VPS37A|Hepatocellular carcinoma-related protein 1|VPS37A|HCRP1

• Gene ID:

  137492

• UniProt:

  Q8NEZ2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  vacuolar protein sorting 37 homolog A

• Target:

  VPS37A

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  44 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• CAS Number:

  9007-83-4