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VPS33B antibody

CAT: 0710-FNab09436Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09436Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages (PubMed:18474358) . Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753) . Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity) .
Synonyms
Vacuolar protein sorting-associated protein 33B (hVPS33B) |VPS33B
Gene ID
26276
UniProt
Q9H267
Host
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Vacuolar protein sorting 33 homolog B (yeast)
Target
VPS33B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
71 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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