USP21 antibody

CAT: 0710-FNab09318Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab09318Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di-and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity) . Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates (PubMed:10799498) . Deubiquitinates BAZ2A/TIP5 leading to its stabilization (PubMed:26100909) .
Synonyms
Ubiquitin carboxyl-terminal hydrolase 21|Deubiquitinating enzyme 21|Ubiquitin thioesterase 21|Ubiquitin-specific-processing protease 21|USP21|USP23
Gene ID
27005
UniProt
Q9UK80
Host
Rabbit
Reactivity
Human
Immunogen
Ubiquitin specific peptidase 21
Target
USP21
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
63 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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