SETDB1 antibody

• Background :

  This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

• Synonyms :

  Histone-lysine N-methyltransferase SETDB1|ERG-associated protein with SET domain (ESET) |Histone H3-K9 methyltransferase 4 (H3-K9-HMTase 4) |Lysine N-methyltransferase 1E|SET domain bifurcated 1|SETDB1|ESET|KIAA0067|KMT1E

• Gene ID :

  9869

• UniProt :

  Q15047

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  SET domain, bifurcated 1

• Target :

  SETDB1

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Epigenetics, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  210 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC