SETDB1 antibody

CAT: 0710-FNab07771Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab07771Size:100 µg
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Background
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
Synonyms
Histone-lysine N-methyltransferase SETDB1|ERG-associated protein with SET domain (ESET) |Histone H3-K9 methyltransferase 4 (H3-K9-HMTase 4) |Lysine N-methyltransferase 1E|SET domain bifurcated 1|SETDB1|ESET|KIAA0067|KMT1E
Gene ID
9869
UniProt
Q15047
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SET domain, bifurcated 1
Target
SETDB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
210 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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