SETD6 antibody

• Background :

  Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity (PubMed:21131967) . Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (PubMed:23324626) . Required for the maintenance of embryonic stem cell self-renewal (By similarity) .

• Synonyms :

  N-lysine methyltransferase SETD6|SET domain-containing protein 6|SETD6

• Gene ID :

  79918

• UniProt :

  Q8TBK2

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  SET domain containing 6

• Target :

  SETD6

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB

• Field of Research :

  Epigenetics

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  53 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB