Products for Research Use Only
RegisterLogin

Pre-IL18 antibody

CAT: 0710-FNab06764Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab06764Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release interferon gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 24 kDa precursor and then cleaved into a biologically activate 18 kDa form. This antibody is raised against the full length IL18 precursor, and it recognizes both the pre-IL18 and mature IL18 theoretically.
Synonyms
Interleukin-18 (IL-18) |Iboctadekin|Interferon gamma-inducing factor (IFN-gamma-inducing factor) |Interleukin-1 gamma (IL-1 gamma) |IL18|IGIF|IL1F4
UniProt
Q14116
Host
Rabbit
Reactivity
Human, RAT
Immunogen
Interleukin 18 (interferon-gamma-inducing factor)
Target
Pre-IL18
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP, IHC, IF
Field of Research
Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:5000 ; IHC: 1:50-1:500; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
24 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP, IHC, IF

UniProtKB · Q14116

Interleukin-18

IL18_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14116
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL18
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-18
EC number
—
Processing
Precursor
Secondary accessions
O75599, Q6FGY3, Q6WWJ7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Cytokine

Cellular component

CytoplasmSecreted

Biological process

Inflammatory response

Related Products

CatalogName
EH4111Human Pre-S1 ELISA Kit
FNab04234IL19 antibody
FNab10861IL16 antibody
FNab04212IL10 antibody
FNab04208IL1A antibody
FNab04216IL11 antibody
FNab04235IL19 antibody
FNab04211IL10 antibody
FNab04210IL1B antibody
FNab10822Il10 antibody

Alternative Products

CatalogName
abx236765Pre-IL18 Antibody
PAab06764Anti-Pre-IL18 antibody
E53M02097Pre-IL18 Monoclonal Antibody
GTR18030459-01Pre IL18 Mouse Monoclonal Antibody
GTR18030458-01Pre IL18 Rabbit Polyclonal Antibody
70R-33142IL18 antibody
513107Pre-IL18 discontinued
MBS7602998-01Pre-IL18 Mouse Monoclonal
EF008650Human Pre-IL18 ELISA KIT
HY-RS06708IL18 Human Pre-designed siRNA Set A

Popular Products